荷兰Utrecht大学生物化学博士后岗位
来源：丁香人才网
日期：2008-07-21
Institution
Utrecht University (http://www.uu.nl)
Position
Postdoc Biochemistry
Location
Utrecht, The Netherlands
Date Posted
July 18th 2008
Date Expires
August 25th 2008
Tags
postdoc, biochemistry, utrecht, and the netherlands
Description
The Faculty of Veterinary Medicine (www.vet.uu.nl) is an internationallyleading institute in veterinary scientific education, research andassociated patient care. It ranks number one in Europe and among the topfive institutes of veterinary science world-wide and is accredited bythe American Medical Veterinary Association and the Canadian MedicalVeterinary Association.
The Department of Biochemistry and Cell Biology invites applications for a
Postdoc Biochemistry (m/f) (1,0 fte)
Task
Because pathogens become increasingly resistant to therapeutic drugs,and due to the emergence of new pathogens, novel approaches to thetreatment of infectious diseases are required. By chemical cross-linkingwe have generated bifunctional proteins consisting of a lectin domainand a fragment of an antibody directed against Fc receptors onphagocytic cells. Studies in vitro in our laboratory have shown thatsuch bifunctional proteins can stimulate uptake and killing of a broadspectrum of pathogens by recognizing the microbes through the lectindomain and targeting them to the phagocytes through the anti-Fc receptorpart. Your task will be to expand this work by:
1) varying the anti-Fc receptor moiety,
2) developing a method for the production of the bifunctional proteinsas fusion proteins, and
3) studying the effect of the bifunctional proteins in mouse infectionexperiments in vivo.
We are looking for a biochemist, or medical molecular biologist, holdinga PhD degree, who has experience with molecular biology, proteinexpression and various protein purification techniques, and who hasaffinity with immunology. Experience with mouse infection models and/orpossession of Article 9 certificate to work with laboratory animals isan advantage. Candidates from the European Union are eligible for thisposition. Applications from the American continent will also be considered.
We offer an experienced, collaborative and international group ofcolleagues and an excellent infrastructure that integrates molecularbiology, biochemistry, life-cell imaging, and a state of the artslipidomics facility. We take part in the Institute of Biomembranes(http://www.biomembranes.nl), the Academic Biomedical Centre(http://www.abc.uu.nl) and are engaged in many (inter)national collaborations.
We offer a fulltime temporary appointment for 2 years.
Your gross salary will amount between € 2,802 and € 3,678 per month(full-time appointment in scale 10 of the Collective Labor Agreement ofthe Dutch Universities), depending on previous qualifications andexperience. There are outstanding secondary benefits, based on the CAOof Netherlands Universities and include e.g. a minimum of 31 daysholiday per year, an arrangement for study facilities, generouscontributions to healthcare, childcare, a pension scheme and flexibleemployment conditions.
Contact
Informal inquiries should be directed to Dr. J.J. Batenburg (+31 302535381; e-mail j.j.batenburg@uu.nl).
Application
Please send your application (including a cover letter, a CV, astatement of education, research interests and experimental methodsused, and a detailed list of publications and achievements) before25-08-2008, accompanied by the names and contact info of persons who areable to provide professional reference, under the heading vacancy number12860 to vacatures1@vet.uu.nl, or send your written application byregular mail to Utrecht University, Faculty of Veterinary Medicine,Personnel and Organisation, attn. Mw. M.E.J. Willemse-van Soest,Yalelaan 1, NL 3584 CL Utrecht, The Netherlands.
Utrecht University (http://www.uu.nl)
Position
Postdoc Biochemistry
Location
Utrecht, The Netherlands
Date Posted
July 18th 2008
Date Expires
August 25th 2008
Tags
postdoc, biochemistry, utrecht, and the netherlands
Description
The Faculty of Veterinary Medicine (www.vet.uu.nl) is an internationallyleading institute in veterinary scientific education, research andassociated patient care. It ranks number one in Europe and among the topfive institutes of veterinary science world-wide and is accredited bythe American Medical Veterinary Association and the Canadian MedicalVeterinary Association.
The Department of Biochemistry and Cell Biology invites applications for a
Postdoc Biochemistry (m/f) (1,0 fte)
Task
Because pathogens become increasingly resistant to therapeutic drugs,and due to the emergence of new pathogens, novel approaches to thetreatment of infectious diseases are required. By chemical cross-linkingwe have generated bifunctional proteins consisting of a lectin domainand a fragment of an antibody directed against Fc receptors onphagocytic cells. Studies in vitro in our laboratory have shown thatsuch bifunctional proteins can stimulate uptake and killing of a broadspectrum of pathogens by recognizing the microbes through the lectindomain and targeting them to the phagocytes through the anti-Fc receptorpart. Your task will be to expand this work by:
1) varying the anti-Fc receptor moiety,
2) developing a method for the production of the bifunctional proteinsas fusion proteins, and
3) studying the effect of the bifunctional proteins in mouse infectionexperiments in vivo.
We are looking for a biochemist, or medical molecular biologist, holdinga PhD degree, who has experience with molecular biology, proteinexpression and various protein purification techniques, and who hasaffinity with immunology. Experience with mouse infection models and/orpossession of Article 9 certificate to work with laboratory animals isan advantage. Candidates from the European Union are eligible for thisposition. Applications from the American continent will also be considered.
We offer an experienced, collaborative and international group ofcolleagues and an excellent infrastructure that integrates molecularbiology, biochemistry, life-cell imaging, and a state of the artslipidomics facility. We take part in the Institute of Biomembranes(http://www.biomembranes.nl), the Academic Biomedical Centre(http://www.abc.uu.nl) and are engaged in many (inter)national collaborations.
We offer a fulltime temporary appointment for 2 years.
Your gross salary will amount between € 2,802 and € 3,678 per month(full-time appointment in scale 10 of the Collective Labor Agreement ofthe Dutch Universities), depending on previous qualifications andexperience. There are outstanding secondary benefits, based on the CAOof Netherlands Universities and include e.g. a minimum of 31 daysholiday per year, an arrangement for study facilities, generouscontributions to healthcare, childcare, a pension scheme and flexibleemployment conditions.
Contact
Informal inquiries should be directed to Dr. J.J. Batenburg (+31 302535381; e-mail j.j.batenburg@uu.nl).
Application
Please send your application (including a cover letter, a CV, astatement of education, research interests and experimental methodsused, and a detailed list of publications and achievements) before25-08-2008, accompanied by the names and contact info of persons who areable to provide professional reference, under the heading vacancy number12860 to vacatures1@vet.uu.nl, or send your written application byregular mail to Utrecht University, Faculty of Veterinary Medicine,Personnel and Organisation, attn. Mw. M.E.J. Willemse-van Soest,Yalelaan 1, NL 3584 CL Utrecht, The Netherlands.
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