加州Burnharm医学研究所蛋白丢失性肠病分子机制研究博士后岗位
来源：丁香人才网
日期：2008-03-04
Institution
Burnham Institute for Medical Research
Position
Postdoc Position, MOLECULAR MECHANISMS OF HUMAN DISEASE
Location
CA - California
Date Posted
March 1st 2008
Tags
Biology, Biochemistry, Cell Biology, Genetics, Molecular Biology, Physiology
Description
MOLECULAR MECHANISMS OF HUMAN DISEASE
Highly motivated postdoctoral associate needed to study molecularmechanisms of protein-losing enteropathy (PLE). We showed that synergyof cytokine challenge, increased venous pressure, and loss of heparansulfate from intestinal cells (Bode, et al JCI, 2008), all contribute toPLE. We provided an explanation for heparin therapy in PLE patients(Nature Clinical Practice, 2008).
Experimental systems include cell monolayers, mucosal explants, andmouse models of PLE. Methods cover biochemical analysis of cell-surfaceproteins, gene expression profiling, and analysis of signaling pathwaysactivated during PLE-inducing stress.
Requirements: PhD/MD with strong background in biochemistry, molecularand cell biology, and routine mouse work is required. Experience inintestinal physiology, animal surgery, and Glycobiology preferred.Publications, fluent spoken English, and an interactive, enthusiasticteam spirit are essential for success in the project.
Contact
Send CV and names/contact information of 4 recent references to:
Hudson Freeze PhD
Email: Hudson@burnham.org
Burnham Institute for Medical Research
10901 N. Torrey Pines Rd.
La Jolla, CA 92037
Ph: 858-646-3142
Burnham Institute for Medical Research
Position
Postdoc Position, MOLECULAR MECHANISMS OF HUMAN DISEASE
Location
CA - California
Date Posted
March 1st 2008
Tags
Biology, Biochemistry, Cell Biology, Genetics, Molecular Biology, Physiology
Description
MOLECULAR MECHANISMS OF HUMAN DISEASE
Highly motivated postdoctoral associate needed to study molecularmechanisms of protein-losing enteropathy (PLE). We showed that synergyof cytokine challenge, increased venous pressure, and loss of heparansulfate from intestinal cells (Bode, et al JCI, 2008), all contribute toPLE. We provided an explanation for heparin therapy in PLE patients(Nature Clinical Practice, 2008).
Experimental systems include cell monolayers, mucosal explants, andmouse models of PLE. Methods cover biochemical analysis of cell-surfaceproteins, gene expression profiling, and analysis of signaling pathwaysactivated during PLE-inducing stress.
Requirements: PhD/MD with strong background in biochemistry, molecularand cell biology, and routine mouse work is required. Experience inintestinal physiology, animal surgery, and Glycobiology preferred.Publications, fluent spoken English, and an interactive, enthusiasticteam spirit are essential for success in the project.
Contact
Send CV and names/contact information of 4 recent references to:
Hudson Freeze PhD
Email: Hudson@burnham.org
Burnham Institute for Medical Research
10901 N. Torrey Pines Rd.
La Jolla, CA 92037
Ph: 858-646-3142
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