资讯分类

英国牛津大学心脏发育研究博士后岗位

日期:2008-02-28
Institution

University of Oxford (http://www.ox.ac.uk)

Position

Postdoctoral Research Fellow

Location

Oxford, United Kingdom

Date Posted

February 27th 2008

Date Expires

March 21, 2008

Tags

genetics and genomics, molecular biology, cell biology, proteomics, andbiological sciences

Description

University of Oxford

Department of Cardiovascular Medicine
Wellcome Trust Centre for Human Genetics

Postdoctoral Research Fellow
£26,666 – £32,796 p.a.

Transcriptional & epigenetic mechanisms in cardiac development.

Congenital heart disease (CHD) is a major birth defect that has aworldwide disease burden exceeding that of diabetes and results fromboth genetic and environmental factors. Our laboratory(www.well.ox.ac.uk/bhattacharya/) uses an interdisciplinary approachcombining high-throughput genetics and magnetic resonance imaging toidentify the genetic and gene-environment interactions underlying CHD. Aparticular interest is transcriptional regulation and the molecularmechanisms underlying genetic buffering.

We are seeking to recruit a postdoctoral research fellow with experiencein transcriptional regulation who would use cellular and molecularapproaches to complement these studies. These include analysis oftranscriptional mechanisms in cells and developing embryos; how theseare disrupted by human mutations and environmental modifiers;genome-wide epigenetic approaches (e.g. ChIP-on-chip, MeDIP); analysisof protein complexes using mass spectrometry. Expertise in massspectrometry and proteomics would be an advantage and you would beexpected to interact closely with the adjacent proteomics core facility(DrBenedikt Kessler, E-mail: bmk@ccmp.ox.ac.uk

http://www.ccmp.ox.ac.uk/kessler/cpf.htm). The fellow will ideally havea PhD and at least 2 years post-doctoral experience and publications inthe field and will be encouraged to apply for further grantfunding/independent fellowships to develop their career.

The Wellcome Trust Centre for Human Genetics provides excellent genomic& proteomic core facilities and opportunities for interactions withmolecular biologists & geneticists. The appointment is availablefrom 1 May 2008 or as soon as possible thereafter. The studies arefunded by a Wellcome Trust Programme Grant for 5 years.

Contact

Further particulars, which detail the application procedure, should beobtained from http://www.admin.ox.ac.uk/fp/ The closing date forapplications is 21 March 2008. Please contact Professor ShoumoBhattacharya e-mail: sbhattac@well.ox.ac.uk to informally discuss the post.

As an Equal Opportunity employer, we positively encourage applicationsfrom people of all backgrounds

http://www.ox.ac.uk/jobs
[作者:jurgen    编辑:]