纽约阿尔伯特爱因斯坦医学院基因重排研究博士后岗位
来源：丁香人才网
日期：2008-01-02
Institution
Albert Einstein Collete of Medicine
Position
POSTDOCTORAL FELLOW
Location
Greater NYC
Date Posted
Dec 28th 2007
Description
POSTDOCTORAL FELLOW : When somatic cells are induced to becomepluripotent stem (iPS) cells, global epigenetic remodeling occurs anddramatic reprogramming of DNA replication is required. Our laboratoryfocuses on the fidelity, mechanism, and requirements for DNA replicationreprogramming using several genomic loci as model systems.
We use high-resolution microarrays and Solexa sequencing on the genomicscale. Chromatin immunoprecipitation (ChIP) in combination withmicroarrays (ChIP-on-chip) is being used to determine the role ofhistone modifications in regulating the DNA replication program. Therole of replication initiation sites in reprogramming loci critical fordevelopment is being studied by analysis of single DNA molecules.
Additional Projects include:
• Reprogramming of DNA replication by modification of chromatin structure.
• Changes in nuclear organization and DNA replication during B celldevelopment and their role in immunoglobulin heavy chain gene rearrangement.
For more information please visit –
http://www.aecom.yu.edu/cellbiology/schildkraut.htm
The Department of Cell Biology at the Albert Einstein College ofMedicine has initiated a special awards program for outstandingcandidates. The awards carry a stipend of $50,000/year for three years.Applicants to my laboratory would be eligible to apply; however,long-term NIH funding is available for an applicant who does not receivethis award.
These studies are being carried out in the Einstein Center for HumanEmbryonic Stem Cell Research. The Albert Einstein College of Medicine islocated in a pleasant, quiet residential area in the northeast corner ofNew York City with easy access to Manhattan and the suburbs ofWestchester County and Connecticut. Affordable University housing isavailable close to the campus.
Contact
Applicants with a Ph.D., and/or M.D., who are highly motivated with astrong background in molecular, stem cell, and/or cancer biology orbiochemistry are encouraged to apply.
Please send CV, brief statement of research interests and names of threereferences to:
Dr. Carl Schildkraut
Department of Cell Biology
Albert Einstein College of Medicine
1300 Morris Park Avenue
New York, New York 10461
Email address schildkr@aecom.yu.edu
Albert Einstein Collete of Medicine
Position
POSTDOCTORAL FELLOW
Location
Greater NYC
Date Posted
Dec 28th 2007
Description
POSTDOCTORAL FELLOW : When somatic cells are induced to becomepluripotent stem (iPS) cells, global epigenetic remodeling occurs anddramatic reprogramming of DNA replication is required. Our laboratoryfocuses on the fidelity, mechanism, and requirements for DNA replicationreprogramming using several genomic loci as model systems.
We use high-resolution microarrays and Solexa sequencing on the genomicscale. Chromatin immunoprecipitation (ChIP) in combination withmicroarrays (ChIP-on-chip) is being used to determine the role ofhistone modifications in regulating the DNA replication program. Therole of replication initiation sites in reprogramming loci critical fordevelopment is being studied by analysis of single DNA molecules.
Additional Projects include:
• Reprogramming of DNA replication by modification of chromatin structure.
• Changes in nuclear organization and DNA replication during B celldevelopment and their role in immunoglobulin heavy chain gene rearrangement.
For more information please visit –
http://www.aecom.yu.edu/cellbiology/schildkraut.htm
The Department of Cell Biology at the Albert Einstein College ofMedicine has initiated a special awards program for outstandingcandidates. The awards carry a stipend of $50,000/year for three years.Applicants to my laboratory would be eligible to apply; however,long-term NIH funding is available for an applicant who does not receivethis award.
These studies are being carried out in the Einstein Center for HumanEmbryonic Stem Cell Research. The Albert Einstein College of Medicine islocated in a pleasant, quiet residential area in the northeast corner ofNew York City with easy access to Manhattan and the suburbs ofWestchester County and Connecticut. Affordable University housing isavailable close to the campus.
Contact
Applicants with a Ph.D., and/or M.D., who are highly motivated with astrong background in molecular, stem cell, and/or cancer biology orbiochemistry are encouraged to apply.
Please send CV, brief statement of research interests and names of threereferences to:
Dr. Carl Schildkraut
Department of Cell Biology
Albert Einstein College of Medicine
1300 Morris Park Avenue
New York, New York 10461
Email address schildkr@aecom.yu.edu
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