资讯分类

芝加哥大学上皮细胞生物学研究博士后岗位

日期:2007-11-28
Institution

The University of Chicago

Position

Postdoctoral positions available in epithelial cell biology

Location

Chicago, IL, USA

Date Posted

Nove 27th 2007

Description

Project 1 (Dr. Zegers) investigates the molecular mechanisms regulatingepithelial cell morphogenesis during wound healing and inthree-dimensional culture systems. The research focuses primarily on thequestion of how the direct extracellular environment of epithelial cellsregulates processes like cell polarization, cell migration andproliferation. We specifically focus on the role of Rho effectorproteins in cell-cell and cell-matrix mediated signaling pathways.

Project 2 (Dr. ter Beest) investigates the role of intracellularmembrane trafficking in epithelial membrane polarity in two andthree-dimensional culture systems. In addition, we are interested howcellular transformation affects intracellular membrane transport and howthis contributes to loss in membrane polarity. We are focusing on therole of SNARE proteins and small GTPases in these processes.

Experimental approaches include two- and three dimensional cell culturemodel systems, laser confocal microscopy and biochemical and molecularbiology techniques.

Qualified candidates should have a recent Ph.D. or equivalent degree inCell Biololgy or related field, be motivated, organized, and able towork independently. Knowledge of techniques in cell biology andmolecular biology is required. Candidates should have a good command ofthe English language and should be available for an interview. Onlycandidates with proven track of publication in international peerreviewed journals can apply.

Contact

Please send via e-mail a current CV, statement of research interests,and names and contact information of three references to Dr. MirjamZegers (mzegers@uchicago.edu) or Dr. Martin ter Beest (mterbeest@uchicago.edu).
[作者:jurgen    编辑:]