Pennsylvania大学肿瘤研究博士后
Postdoctoral Fellow : Philadelphia, PA, USA
Employers:
The University of Pennsylvania
Location(s):
Philadelphia, PA, USA
Posted:
September 21, 2010
Expires:
November 20, 2010
Website:
Job Tag(s):
cance,stem cells,tumor biology,squamous,cell carcinoma,head and neck esophagus
Description:
A postdoctoral position is available immediately in the area of cancer biology. The position is within the laboratory of Dr. Meenhard Herlyn at the Wistar Institute and will be in close affiliation with the Department of Otorhinolaryngology-Head and Neck Surgery at the University of Pennsylvania. Candidates are sought to join a basic and translational research program focusing on squamous cell carcinomas of the upper aerodigestive tract, recently funded by an NCI P01 grant. This program aims to identify mechanisms of therapy resistance in these malignancies and develop novel approaches to targeting tumor cell subpopulations resistant to current chemotherapeutic agents. Our overall strategy is to define and target not only the drug-resistant tumor cell subpopulations themselves but also critical interactions with the stromal microenvironment that modulate their resistant phenotypes. Studies will rely upon our laboratory’s extensive experience in 3-dimensional in vitro cancer models and in vivo xenograft models, in addition to utilizing readily available patient-derived tumor specimens. Work will be performed under mentorship from Dr. Herlyn, and the position will be supported by Dr. Devraj Basu in the Department of Otorhinolaryngology.
Contact:
Interested individuals should send cover letter, CV, and reference information (by e-mail) to:
Meenhard Herlyn, D.V.M., D.Sc.
Professor and Program Leader, Molecular and Cellular Oncogenesis Program
Wistar Institute Cancer Center
3601 Spruce St.
Philadelphia, PA 19104
Devraj Basu, MD, PhD, FACS
Assistant Professor
Division of Head and Neck Surgery
Dept. Otorhinolaryngology:Head and Neck Surgery
University of Pennsylvania Health System
emails:
herlynm@wistar.org
devraj.basu@uphs.upenn.edu
215-898-3950, Office
215-898-0980, Fax