加州大学洛杉矶分校分子生物学博士后

Postdoc or Research Faculty in Molecular Mechanisms of Disease : Los Angeles

Employers:

University of California, Los Angeles (UCLA)

Location(s):

Los Angeles

Posted:

July 07, 2010

Expires:

July 06, 2011

Job Tag(s):

neurodegenerative diseases,human diseases,molecular mechanisms,cell biology,genetics,genomics

Description:

We seek enthusiastic and motivated postdoctoral fellow or research faculty to study molecular mechanisms underlying Neurodegenerative diseases including Parkinson’s and Alzheimer’s disease. Areas of interest include mitochondrial biology, mechanisms of neuronal death (apoptosis and autophagy), protein trafficking, developmental biology, neurobiology and 3D computer reconstruction brain imaging. Postdoctoral candidates should hold recent Ph.D. and/or MD degrees. Research faculty candidates are expected to have multiple recent publications.
For our work, please see:

Clark I.E., Dodson M.W., Jiang C.*, Cao J.H., Huh J.R., Seol J., Yoo S., Hay, B.A. and Guo, M. (2006) Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature, 441: 1162-1166.

Deng, H., Dodson, M.W., Huang, H. and Guo, M. (2008) The Parkinson’s disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila. PNAS, 105: 14503-14508.

Yun, J., Cao, J.H., Dodson, M.W., Clark, I.E., Kapahi, P., Chowdhury, R.B. and Guo, M. (2008) Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the pink1/parkin pathway in vivo. J. Neurosci.

Gross, G., Feldman, R.M., Ganguly, A., Wang, J.H., Yu, H. and Guo, M. (2008) Role of X11 and ubiquilin as in vivo regulators of the Amyloid Precursor Protein in Drosophila. PLoS ONE, 3(6):e2495.

Ganguly, A., Feldman, R.M., and Guo, M. (2008) ubiquilin antagonizes presenilin and promotes neurodegeneration. Hum. Mol. Genet. 17:293-302.

Hay, B.A. and Guo, M. (2006) Caspase-Dependent Cell Death in Drosophila. Annu. Rev. Cell Dev. Biol., 22: 623-650.

Contact:

Send curriculum vitae, a cover letter stating past research and career goals, as well as names of three references to:

Ming Guo, MD, PhD
Associate Professor
Department of Neurology
Department of Molecular & Medical Pharmacology
Brain Research Institute,
Gonda Center for Neuroscience and Genetics
UCLA David Geffen School of Medicine
Los Angeles, CA 90095
E-mail: uclaflylab@yahoo.com