资讯分类

耶鲁大学医学院基因稳定和肿瘤预防研究博士后岗位

日期:2008-05-23
Institution

Yale University School of Medicine (http://radonc.yale.edu/)

Position

postdoctoral position

Location

New Haven, Connecticut, USA

Date Posted

May 22th 2008

Date Expires

July 21th 2008

Tags

postdoc, postdoctoral, cancer, biochemistry, aging, cell biology, newhaven, connecticut, and usa

Description

Postdoctoral positions are now available at Yale University School ofMedicine. The research focus will relate to studies of the molecularmechanisms of genome maintenance and cancer prevention by the human RecQfamily proteins. The projects will center on (1) identifying RecQprotein complexes from mammalian cell extracts, (2) characterizing invitro biochemical properties of the RecQ protein complexes, (3)understanding in vivo cellular roles of the RecQ complexes, and (4) howthe RecQ protein complexes are regulated in response to DNA damage andcell-cycle. For more information on human RecQ helicases and the relatedclinical diseases, please visit:
http://radonc.yale.edu/faculty/liu.html

Contact

Candidates MUST be U.S. citizens or permanent residents (Green Cardholders). Candidates must hold a Ph.D. degree or equivalent by thestarting date. Experience in protein biochemistry is strongly desirable.Please submit curriculum vitae and three letters of reference to:

Yilun Liu, Ph.D.
Assistant Professor
Department of Therapeutic Radiology
Yale University School of Medicine
New Haven, CT 06510
Email: yilun.liu@yale.edu

Selected publications from Dr. Yilun Liu:
(1) Aygun O, Svejstrup J & Liu Y (2008) PNAS, in press
(2) Liu Y, Tarsounas M, O’Regan P & West, SC (2007) J Biol Chem 282, 1973-1979
(3) McIlwraith MJ, Vaisman A, Liu Y, Fanning E, Woodgate R & West,SC (2005) Mol Cell 20, 783-792
(4) Esashi F, Chris N, Gannon J, Liu Y, Hunt T, Jasin M & West SC(2005) Nature 434, 598-604
(5) Liu Y & West SC (2004) Nature Rev in Mol Cell Biol 5, 937-944
(6) Liu Y, Masson JY, Shah R, O’Regan P & West SC (2004) Science303, 243-246
(7) Garcia LP, Liu Y, Jiricny J, West, SC & Janscak P (2004) EMBO J23, 2882-2891
(8) Liu Y & West SC (2002) Breast Cancer Res 4, 9-13
(9) Singleton MR, Wentzell LM, Liu Y, West SC & Wigley DB (2002)PNAS 99, 13492-13497
(10) Liu Y & Maizels N (2000) EMBO R 1, 85-90
(11) Liu Y, Li MJ, Lee EY & Maizels N (1999) Curr Biol 9, 975-978
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