辛辛那提儿童医院研究基金会发育生物学研究博士后岗位
来源：丁香人才网
日期：2008-05-20
Institution
Division of Developmental Biology, Cincinnati Children's HospitalResearch Foundation (http://www.cincinnatichildren...)
Position
Postdoctoral Position-Study of a Gap Junction Network Required for theEstablishment of Left-Right Neuronal Asymmetry
Location
Cincinnati, OH, USA
Date Posted
May 17th 2008
Date Expires
December 31th 2008
Tags
postdoctoral, Phd, genetics, cell biology, molecular biology,neurobiology, biochemistry, cincinnati childrens hospital researchfoundation, cincinnati, oh, and usa
Description
Gap junctions are prominent features that link immature cells in thenervous system of both invertebrates and vertebrates. However, little isknown about the functional consequences of these interactions. Werecently showed for the first time that signaling through gap junctionscoordinates a network of cells to establish left-right asymmetry in thenervous system of C. elegans that is reflected in olfactory geneexpression and function (Chuang et. al., Cell 2007). We are interestedin understanding the molecular mechanisms of left-right neuronalasymmetry by this gap junction-dependent cell network. To learn moreabout the lab, please visit
http://www.cincinnatichildrens.org/research/div/dev-biology/fac-labs/chuang/
http://neuroscience.uc.edu/faculty/person.cfm?NeuroID=180
Contact
Applicants should have a Ph.D. degree (for less than three years) ingenetics, cell biology, molecular biology, neurobiology, biochemistry orsimilar with experience in molecular biology techniques. Candidates withprior experience in electrophysiological recordings or calcium imagingor microarray are encouraged to apply. Interested and qualifiedcandidates please send a brief cover letter describing researchexperience and interest, CV, and names and contact information of atleast two references to Dr. Chiou-Fen Chuang at Chiou-Fen.Chuang@cchmc.org.
References:
Chuang, C.-F., VanHoven, M. K., Fetter, R. D., Verselis, V. K., andBargmann, C. I. (2007). An innexin-dependent cell network establishesleft-right neuronal asymmetry in C. elegans. Cell 129, 787-799.
Chuang, C.-F. and Bargmann, C. I. (2005). A Toll-interleukin 1 repeatprotein at the synapse specifies asymmetric odorant receptor expressionvia ASK1 MAPKKK signaling. Genes & Dev. 19, 270-281. (http://www.genesdev.org/cgi/content/full/19/2/270)
Division of Developmental Biology, Cincinnati Children's HospitalResearch Foundation (http://www.cincinnatichildren...)
Position
Postdoctoral Position-Study of a Gap Junction Network Required for theEstablishment of Left-Right Neuronal Asymmetry
Location
Cincinnati, OH, USA
Date Posted
May 17th 2008
Date Expires
December 31th 2008
Tags
postdoctoral, Phd, genetics, cell biology, molecular biology,neurobiology, biochemistry, cincinnati childrens hospital researchfoundation, cincinnati, oh, and usa
Description
Gap junctions are prominent features that link immature cells in thenervous system of both invertebrates and vertebrates. However, little isknown about the functional consequences of these interactions. Werecently showed for the first time that signaling through gap junctionscoordinates a network of cells to establish left-right asymmetry in thenervous system of C. elegans that is reflected in olfactory geneexpression and function (Chuang et. al., Cell 2007). We are interestedin understanding the molecular mechanisms of left-right neuronalasymmetry by this gap junction-dependent cell network. To learn moreabout the lab, please visit
http://www.cincinnatichildrens.org/research/div/dev-biology/fac-labs/chuang/
http://neuroscience.uc.edu/faculty/person.cfm?NeuroID=180
Contact
Applicants should have a Ph.D. degree (for less than three years) ingenetics, cell biology, molecular biology, neurobiology, biochemistry orsimilar with experience in molecular biology techniques. Candidates withprior experience in electrophysiological recordings or calcium imagingor microarray are encouraged to apply. Interested and qualifiedcandidates please send a brief cover letter describing researchexperience and interest, CV, and names and contact information of atleast two references to Dr. Chiou-Fen Chuang at Chiou-Fen.Chuang@cchmc.org.
References:
Chuang, C.-F., VanHoven, M. K., Fetter, R. D., Verselis, V. K., andBargmann, C. I. (2007). An innexin-dependent cell network establishesleft-right neuronal asymmetry in C. elegans. Cell 129, 787-799.
Chuang, C.-F. and Bargmann, C. I. (2005). A Toll-interleukin 1 repeatprotein at the synapse specifies asymmetric odorant receptor expressionvia ASK1 MAPKKK signaling. Genes & Dev. 19, 270-281. (http://www.genesdev.org/cgi/content/full/19/2/270)
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