德国沃尔兹堡大学神经系统免疫调节研究博士后岗位
来源：丁香人才网
日期：2008-04-18
Institution
University of Wuerzburg
Position
Postdoctoral position: immuneregulation in the CNS
Job Number
4003218
Date Posted
Apr 16th 2008
Application Deadline
May 31th 2008
Description
Call for applications for a postdoctoral position: immuneregulation inthe CNS (TV-L equivalent to BATIIa)
A postdoctoral position is currently available at the Clinical ResearchGroup for MS and Neuroimmunology located at the University of Wuerzburg,Department of Neurology. We are looking for a creative and motivatedpostdoc with ambitious career interest and experience in immunology.
The work is related to the fundamental mechanisms of immune regulationin the central nervous system, especially the role of novel coinhibitorymolecules of the B7-family and the interaction of CNS-antigen-presentingrelation with regulatory T cells. Approaches cover experimental animalmodels using conditional transgenes and ablatable systems as well asvarious techniques in human cellular and molecular immunology.
The work is funded by the Deutsche Forschungsgemeinschaft DFG as part ofthe Sonderforschungsbereich 581 (Molecular models of nervous system diseases).
Recent literature:
Magnus T, Schreiner B, Korn T, Jack C, Hong G, Antel J, Ifergan I, ChenL, Bischof F, Bar-Or A, Wiendl H. Microglial expression of the B7-familymember B7-H1 confers strong immune inhibition: implications for immuneresponses and autoimmunity in the CNS. J Neuroscience 2005; 25(10):2537-2546
Feger U, Tolosa E, Huang Y, Waschbisch A, Biedermann T, Melms A, WiendlH. HLA-G expression defines a novel regulatory T cell subset present inhuman peripheral blood and sites of inflammation. Blood. 2007; 110(2):568-77
Meuth SG, Bittner S, Meuth P, Simon OJ, Budde T, Wiendl H. TWIK-relatedacid sensitive K+ channel 1 (TASK1) and TASK3 critically influence Tlymphocyte effector functions. J Biol Chem. 2008; Epub ahead of print
Zozulya A, Wiendl H. Mechanisms of disease: the role of regulatory Tcells and dendritic cells in Multiple sclerosis. Nature Reviews ClinPractice, In press
Lafon M, Megret F, Meuth SG, Romero M, Lafage M, Chen L, Aleopoulou L,Flavell R, Prehaud C, Wiendl H. Detrimental contribution of theimmunoinhibitor B7-H1 to rabies virus encephalitis. J Immunol. In press
Ortler S, Leder C, Mittelbronn M, Zozulya A, Knolle P, Chen L, Kroner A,Wiendl H. B7-H1 modulates neuroantigen-specific T cell responses andconfines inflammatory CNS damage: implications for the lesionpathogenesis of Multiple sclerosis. Eur J Immunol. In press
Contact
Please send a letter of application including curriculum vitae,certificates and names and addresses of potential referees to:
Heinz Wiendl, MD
Professor of Neurology and Head of the Clinical Research Group forMultiple Sclerosis and Neuroimmunology
Department of Neurology, University of Wuerzburg
Josef-Schneider-Straße 11
97080 Wuerzburg
Germany
Tel.: + 49-931-201-23755
Fax.: + 49-931-201-23488
E-mail: heinz.wiendl@klinik.uni-wuerzburg.de
Secretary for the Clinical Research Group for MS and Neuroimmunology
Tel.: +49-9 31-2 01-2 37 56
University of Wuerzburg
Position
Postdoctoral position: immuneregulation in the CNS
Job Number
4003218
Date Posted
Apr 16th 2008
Application Deadline
May 31th 2008
Description
Call for applications for a postdoctoral position: immuneregulation inthe CNS (TV-L equivalent to BATIIa)
A postdoctoral position is currently available at the Clinical ResearchGroup for MS and Neuroimmunology located at the University of Wuerzburg,Department of Neurology. We are looking for a creative and motivatedpostdoc with ambitious career interest and experience in immunology.
The work is related to the fundamental mechanisms of immune regulationin the central nervous system, especially the role of novel coinhibitorymolecules of the B7-family and the interaction of CNS-antigen-presentingrelation with regulatory T cells. Approaches cover experimental animalmodels using conditional transgenes and ablatable systems as well asvarious techniques in human cellular and molecular immunology.
The work is funded by the Deutsche Forschungsgemeinschaft DFG as part ofthe Sonderforschungsbereich 581 (Molecular models of nervous system diseases).
Recent literature:
Magnus T, Schreiner B, Korn T, Jack C, Hong G, Antel J, Ifergan I, ChenL, Bischof F, Bar-Or A, Wiendl H. Microglial expression of the B7-familymember B7-H1 confers strong immune inhibition: implications for immuneresponses and autoimmunity in the CNS. J Neuroscience 2005; 25(10):2537-2546
Feger U, Tolosa E, Huang Y, Waschbisch A, Biedermann T, Melms A, WiendlH. HLA-G expression defines a novel regulatory T cell subset present inhuman peripheral blood and sites of inflammation. Blood. 2007; 110(2):568-77
Meuth SG, Bittner S, Meuth P, Simon OJ, Budde T, Wiendl H. TWIK-relatedacid sensitive K+ channel 1 (TASK1) and TASK3 critically influence Tlymphocyte effector functions. J Biol Chem. 2008; Epub ahead of print
Zozulya A, Wiendl H. Mechanisms of disease: the role of regulatory Tcells and dendritic cells in Multiple sclerosis. Nature Reviews ClinPractice, In press
Lafon M, Megret F, Meuth SG, Romero M, Lafage M, Chen L, Aleopoulou L,Flavell R, Prehaud C, Wiendl H. Detrimental contribution of theimmunoinhibitor B7-H1 to rabies virus encephalitis. J Immunol. In press
Ortler S, Leder C, Mittelbronn M, Zozulya A, Knolle P, Chen L, Kroner A,Wiendl H. B7-H1 modulates neuroantigen-specific T cell responses andconfines inflammatory CNS damage: implications for the lesionpathogenesis of Multiple sclerosis. Eur J Immunol. In press
Contact
Please send a letter of application including curriculum vitae,certificates and names and addresses of potential referees to:
Heinz Wiendl, MD
Professor of Neurology and Head of the Clinical Research Group forMultiple Sclerosis and Neuroimmunology
Department of Neurology, University of Wuerzburg
Josef-Schneider-Straße 11
97080 Wuerzburg
Germany
Tel.: + 49-931-201-23755
Fax.: + 49-931-201-23488
E-mail: heinz.wiendl@klinik.uni-wuerzburg.de
Secretary for the Clinical Research Group for MS and Neuroimmunology
Tel.: +49-9 31-2 01-2 37 56
[作者：jurgen 编辑：]