迈阿密大学SiRNA治疗肿瘤研究博士后岗位
来源：丁香人才网
日期：2008-03-27
Institution
University of Miami (http://www.med.miami.edu)
Position
Postdoctoral position
Location
Miami, FL
Date Posted
March 26th 2008
Date Expires
May 25th 2008
Tags
rna therapeutics, cancer immunotherapy, tolerance, aptamers, miami, fl,and usa
Description
The Dodson Institute is dedicated to the development of high-impact andbroadly useful immune-based treatments focusing on cancer, infectiousdiseases, autoimmunity and transplantation.
RNA therapeutics. To develop aptamer and aptamer-siRNA chimaeras astherapeutic agents to modulate immune responses in patients. Twopositions are available:
Position 1: Design of aptamers, siRNAs, and aptamer-targeted siRNAsagainst therapeutic targets. Experience in general molecular biologytechniques and cell culture is mandatory; experience with murine models,protein biochemistry, RNA interference and/or aptamers, is desirable.
Position 2: Develop novel aptamer selection methods employing analyticaltools including capillary electrophoresis separation techniques;experience in organic or analytical chemistry and work with protein orRNA is mandatory.
Cancer. To develop methods to stimulate potent immunity by vaccination,manipulating costimulation, and by overcoming tumor-induced immunesuppression. Two positions are available:
Position 1: Develop strategies to potentiate CD4+ T cell immunity.Experience in cell biology is mandatory; experience in subcellularprotein trafficking and cellular immunology is desirable.
Position 2: Develop strategies to overcome tumor-induced immunesuppression. Experience in cellular immunology is mandatory; experienceusing small animal models is desirable.
Tolerance. To develop methods for the selective elimination ofautoreactive T cells using novel reagents based on RNA aptamers andaptamer-siRNA chimaeras to induce T and B cell tolerance. Experience ingeneral molecular biology techniques and cell culture is mandatory;experience in cellular immunology is desirable.Applicants must havecompleted a PhD, MD or equivalent degree. Only candidates with anextensive and relevant track record of productivity will be considered.
Contact
Applicants should specify the position of interest, email curriculumvitae, statement describing research accomplishments and future researchgoals, relevant reprints, and the names/contact information of threereferences to Dr. Eli Gilboa, University of Miami Miller School ofMedicine, Miami Florida; dmii@med.miami.edu
University of Miami (http://www.med.miami.edu)
Position
Postdoctoral position
Location
Miami, FL
Date Posted
March 26th 2008
Date Expires
May 25th 2008
Tags
rna therapeutics, cancer immunotherapy, tolerance, aptamers, miami, fl,and usa
Description
The Dodson Institute is dedicated to the development of high-impact andbroadly useful immune-based treatments focusing on cancer, infectiousdiseases, autoimmunity and transplantation.
RNA therapeutics. To develop aptamer and aptamer-siRNA chimaeras astherapeutic agents to modulate immune responses in patients. Twopositions are available:
Position 1: Design of aptamers, siRNAs, and aptamer-targeted siRNAsagainst therapeutic targets. Experience in general molecular biologytechniques and cell culture is mandatory; experience with murine models,protein biochemistry, RNA interference and/or aptamers, is desirable.
Position 2: Develop novel aptamer selection methods employing analyticaltools including capillary electrophoresis separation techniques;experience in organic or analytical chemistry and work with protein orRNA is mandatory.
Cancer. To develop methods to stimulate potent immunity by vaccination,manipulating costimulation, and by overcoming tumor-induced immunesuppression. Two positions are available:
Position 1: Develop strategies to potentiate CD4+ T cell immunity.Experience in cell biology is mandatory; experience in subcellularprotein trafficking and cellular immunology is desirable.
Position 2: Develop strategies to overcome tumor-induced immunesuppression. Experience in cellular immunology is mandatory; experienceusing small animal models is desirable.
Tolerance. To develop methods for the selective elimination ofautoreactive T cells using novel reagents based on RNA aptamers andaptamer-siRNA chimaeras to induce T and B cell tolerance. Experience ingeneral molecular biology techniques and cell culture is mandatory;experience in cellular immunology is desirable.Applicants must havecompleted a PhD, MD or equivalent degree. Only candidates with anextensive and relevant track record of productivity will be considered.
Contact
Applicants should specify the position of interest, email curriculumvitae, statement describing research accomplishments and future researchgoals, relevant reprints, and the names/contact information of threereferences to Dr. Eli Gilboa, University of Miami Miller School ofMedicine, Miami Florida; dmii@med.miami.edu
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