瑞典卡罗琳斯卡研究所电生理学博士后岗位
来源：丁香人才网
日期：2008-01-25
Institution
Karolinska Institutet (http://www.neuro.ki.se/)
Position
Postdoctoral fellow, electrophysiology
Location
Stockholm, Sweden
Date Posted
January 24th 2008
Date Expires
June 24th 2008
Description
NEUROPEPTIDE REGULATION OF NETWORK ACTIVITY IN THALAMUS AND CEREBRAL CORTEX
Our research is aimed at determining the factors that help switch theforebrain between sleep and arousal. Specifically, we are interested ininvestigating the role of different neurotransmitters, in particularneuropeptides, in controlling firing pattern in thalamus and cerebralcortex. To this end, we make use of spontaneously active slicepreparations. By using a combination of electrophysiological techniques(extra- and intracellular recordings, patch clamp whole cellrecordings), we can follow the effect of a transmitter from the intactnetwork down to determining the conductances involved. Since networkactivity is the product both of the inherent electrical properties ofthe neurones as well as their synaptic connectivity, we also usehistochemical techniques (in situ hybridisation, immunohistochemistry)to determine the anatomical location of the signalling moleculesinvolved. See also http://www.neuro.ki.se/broberger/
Requirements:
The successful candidate should hold a PhD in neuroscience, proficiencyin spoken and written English and 2+ years experience in whole cellpatch clamp and/or intracellular recording. The position is availableimmediately. Due to local scholarship regulations, candidates must haveearned their PhD at a university outside of Sweden and cannot be Swedish citizens.
Contact
Send application, including description of research accomplishments,technical expertise, CV, publication list, and names and contactinformation of two senior scientists for further reference to Christian.Broberger@ki.se
Karolinska Institutet (http://www.neuro.ki.se/)
Position
Postdoctoral fellow, electrophysiology
Location
Stockholm, Sweden
Date Posted
January 24th 2008
Date Expires
June 24th 2008
Description
NEUROPEPTIDE REGULATION OF NETWORK ACTIVITY IN THALAMUS AND CEREBRAL CORTEX
Our research is aimed at determining the factors that help switch theforebrain between sleep and arousal. Specifically, we are interested ininvestigating the role of different neurotransmitters, in particularneuropeptides, in controlling firing pattern in thalamus and cerebralcortex. To this end, we make use of spontaneously active slicepreparations. By using a combination of electrophysiological techniques(extra- and intracellular recordings, patch clamp whole cellrecordings), we can follow the effect of a transmitter from the intactnetwork down to determining the conductances involved. Since networkactivity is the product both of the inherent electrical properties ofthe neurones as well as their synaptic connectivity, we also usehistochemical techniques (in situ hybridisation, immunohistochemistry)to determine the anatomical location of the signalling moleculesinvolved. See also http://www.neuro.ki.se/broberger/
Requirements:
The successful candidate should hold a PhD in neuroscience, proficiencyin spoken and written English and 2+ years experience in whole cellpatch clamp and/or intracellular recording. The position is availableimmediately. Due to local scholarship regulations, candidates must haveearned their PhD at a university outside of Sweden and cannot be Swedish citizens.
Contact
Send application, including description of research accomplishments,technical expertise, CV, publication list, and names and contactinformation of two senior scientists for further reference to Christian.Broberger@ki.se
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