Job Description The Department of Cancer and Cell Biology at University of Cincinnati has an opening for Postdoctoral Fellow to study transcriptional and epigenetic regulation of gene expression in breast cancer. The Zhang laboratory currently focuses on elucidating molecular mechanisms of gene- and tissue- specific transcriptional cofactors [Mol Cell 19:89-100, PNAS (2010) 107: 6765, PNAS (2010) 107:10196, JBC (2011) 286(20):17746, EMBO J. (2011) 30(12):2405] in mammary stem cells fate determination and breast cancer by using a combination of biochemical, molecular, genomic (RNA-seq, ChIP-seq) as well as mouse genetic (conditional knockout, mutant knockin and overexpression) approaches. We are also currently developing RNA-based nano-therapeutics to target these cofactors to overcome the endocrine and chemo- therapeutic resistance of human breast cancer.
The Zhang laboratory is located at the state-of-art Vontz Center for Molecular Studies of the College of Medicine. The Vontz Center is situated in the Medical Center which includes Cincinnati Children’s Hospital Medical Center, College of Medicine, UC Cancer Institute, University Hospital and Barrett Cancer Center. The medical center is a dynamic and collaborative environment research environment through strong partnerships between Children’s Hospital Medical Center and the University of Cincinnati, with total annual NIH funding ranked in the top 30 of the country. Cincinnati is the 27th big city in the United States and is considered as one of most livable city with affordable cost and favorable climate.
Interested candidates must have a Ph.D. and/or M.D. degree with research experience in biochemistry, molecular or cellular biology. Prior experience with animal studies or RNA-seq/ChIP-seq is a plus. Salary is competitive with an attractive benefits package that includes family health insurance, retirement contributions, etc. If interested, please submit a CV and list of contact information for three references to:
Xiaoting Zhang, Ph.D.
Department of Cancer and Cell Biology
The Vontz Center for Molecular Studies
University of Cincinnati College of Medicine
3125 Eden Avenue
Cincinnati, OH 45267
Office: (513)558-3017
Lab: (513)558-8083
Email: zhangxt@ucmail.uc.edu
Lab Homepage: http://homepages.uc.edu/~zhangxt/index.html
All interested applicants may also apply to position number 212UC3825 via the UC Jobs website: www.jobsatuc.com. | |