资讯分类

佛罗里达州迈阿密大学神经科学和分子生物学研究博士后岗位

日期:2008-04-21
Institution

University of Miami (http://med.miami.edu)

Position

Post Doctoral Associate

Location

Miami, Florida

Date Posted

April 17th 2008

Date Expires

June 16th 2008

Tags

miami, florida, miller school of medicine, postdoc, post doc,neuroscience, and molecular biology

Description

We strive to deliver the best – in patient care, research, andeducation. Experience amazing opportunities and outstanding rewards withthe University of Miami, Miller School of Medicine.

This position is eligible for a $500 Employee Referral Bonus consistentwith the University policy.

The Miami Project to Cure Paralysis provides a vibrant researchenvironment with outstanding core facilities and infrastructure.

A postdoctoral position is available to study the molecular mechanism(s)involved in preventing neurite growth over inhibitory substrates usingin vitro assays and in vivo after spinal cord injury. We are usingprimary neuronal: mixed glial cultures and stripe assays to examine theroles of several intracellular signaling pathways in cellular mechanismsof neuronal growth cone motility and guidance, using advanced live cellimaging, molecular and biochemical approaches. Experiments will involvethe study of signaling intermediaries via FRET/fluorescent-tagging usingviral vectors. Subsequent translation of findings in this assay tospinal cord injury in vivo models will be performed using genetherapeutic strategies with lenti- or adeno-associated viral vectortechnology (including siRNA) and will involve surgery, histology andstereological analysis by computer microscopy. The postdoctoral scholarwill be part of a multi-institutional research group(http://www.miamiproject.miami.edu) which involves frequent interactionswith a broad range of scientists with expertise in human genetics,bioinformatics, molecular biology, immunology, molecular pharmacology,rehabilitative medicine and clinical pathology.

Job Requirements:
Applicant should have a recent Ph.D. in Neuroscience or celltransplantation or related field. Experience in molecular biologicaltechniques is required including RNA and DNA extractions, PCR, RT-PCR,functional promoter assays and cloning. Previous work in primaryneuronal cultures, intracellular second messenger signaling pathways,siRNA and/or CNS injury models is desired. Excellent communication andorganizational skills preferred. Candidates must have published at leastone first author paper in an English language journal. An appropriatecombination of education, certifications, and/or relevant workexperience will be considered.

Discover all this and countless opportunities that reward your talent.The University of Miami, Miller School of Medicine is proud to offerthose who lead with us competitive salaries, medical and dentalbenefits, tuition remission, vacation, university paid holidays and much more.
[作者:jurgen    编辑:]