The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organisations in the world. The Headquarters Laboratory is located in Heidelberg (Germany), with additional sites in Grenoble (France), Hamburg (Germany), Hinxton (UK) and Monterotondo (Italy).
A postdoctoral position is available to structurally and functionally characterize multi-protein complexes involved in RNA polymerase I transcription using the combination of X-ray crystallography, electron microscopy and biochemistry. The project builds onto the recently determined crystal structure of RNA polymerase I (Fernández-Tornero et al., 2013). The successful candidate will join the Christoph Müller group at the Structural and Computational Biology Unit at EMBL Heidelberg. EMBL is a leading international research organization with a collaborative and interdisciplinary atmosphere (seewww.embl.de). The Müller group studies molecular mechanisms of eukaryotic transcriptional regulation.
Qualifications and Experience
We are seeking to recruit an outstanding candidate with strong interest in the characterization of challenging multi-protein complexes using integrated structural biology approaches. The successful candidate holds a Ph.D. in structural biology or biochemistry. Previous experience in the purification and biochemical analysis of multi-protein complexes and/or previous experience in X-ray crystallography or single-particle electron microscopy would be an advantage. The position requires exceptional motivation and commitment, the ability to work independently as well as in a team and excellent technical, organizational and management skills. An initial contract of 3 years will be offered to the successful candidate. This can be renewed, depending on the circumstances….