A postdoctoral position is immediately available in the Neuroimmunology and Multiple Sclerosis Research Section (nims) at the Department of Neurology, University Hospital of Zurich. Nims is a a highly interdisciplinary and international research group that studies the etiology and disease mechanisms of multiple sclerosis (MS). Our research spans several strategic areas ranging from basic immunology to clinical translation. The candidate will have the opportunity to work on a project that aims to identify disease-relevant autoantigens and foreign (viral/bacterial) triggers in MS. The main task of the applicant will be to develop a brain-derived cDNA expression library using autologous B cell lines and to use it to dissect the specificity of relevant pathogenic T cells in MS. The identification of new autoantigens in MS may provide a basis for the development of future antigen-specific tolerization treatments for this disease, which are also pursued within the group.
Applicant are expected to hold a Ph.D. in a biological, biomedical or related discipline. A broad understanding and experience in molecular biology, cellular and molecular immunology and tissue culture techniques are required. A good command of written and spoken English, strong organizational and interpersonal skills, and the ability to work independently are essential.
The initial appointment is for one year and is renewable depending on performance. Salary is highly competitive and commeasurable with experience.
Interested applicants should send a copy of their CV with a publication list, a one page summary of research accomplishments and interests, and contact details of three references to: Mireia.SospedraRamos@usz.ch .